Praziquantel discoveries
Posted: Tue Jan 14, 2014 2:28 pm
Please read this and digest it carefully!!!
Ok here’s the deal with Praziquantel or more specifically 100% pure prazi.
Praziquantel originated in the United States where Tom Holder some years ago marketed Prazipond for Koi which was and is 100% pure prazi. it was originally and still is an equine wormer.
Then several years later came fluksolve which is 50% pure prazi which as you can see is half the strength
Dose rates:
In the States 100% pure prazi is dosed at 10gm per 1000 US gallons or 10 gm per 800 UK gallons as a US gallons is 20% less than ours its quite a strong dose compared to our approach
Flukesolve is dosed at 10gm or 50% concentration for 550 gallons.
Doc Johnson of Koivet advocates 7gm of 100%prazi to 1000 US gallons which equates to 3.5 grams to 400 uk gallons, which if you downscale it to 50% prazi is the same as flukesolve at 10 gm per 550 UK gallons, so doc Johnsons view is more in line with the Uk’s flukesolve does rate.
So it’s a bit confusing but it’s not really if you look at it logically
Now in the USA as well as using a higher dose than us they routinely dose it with Proform C, Proform C is 20% formaldehyde and 1% malachite green premix, this they say screws the flukes and just about every other parasite on the planet at the same time, the reasoning for this is as follows:
Its universally accepted that Prazi is an absolute swine to dissolve end of! And guess what it dissolves readily into? Yes preform c ! Hence some bright sparks some years back discovered you could dissolve 100% prazi into a standard pond dose of Proform c and hit everything at the same time. So it’s been Accepted in the states for years now you can if you wish dissolve one into the and hit multi parasites at the same time. I have spoken to several pond chums over the pond and they all dissolve Prazi into a standard pond dose of Proform C.
So if we come back to the dissolving problem, even flukesolve does not dissolve readily although I believe it’s better than pure prazi. In America if you want to dissolve it WITHOUT Proform c, you put the dose into a plastic litre pop bottle fill it with plain water and shake the whey out of it for 3 minutes and at least 70% of the stuff will dissolve ( this is in the prazipond instruction) then you add this to a bucket of pond water and most of the rest dissolves you then add to the pond and over a day or two you get a total dissolve. But I got to thinking about the proform C /Prazi combination and started to think I wonder if????
Right my thinking was the malachite aspect of the combo was is insignificant in the dissolving process as it’s just a salt, so it had to be the formaldehyde so I set about seeing how little you could get away with and came up with this formula
5 grams of Prazi + 5 ml of formaldehyde plus 5 ml of water mix this with vigour for 2 to 3 minutes and you get a white free flowing paste, let it stand for a 5 minutes then top up with tap water stirring as you add water and you will find you have totally dissolved the powder 100% add this to a buck of pond water and mix then spread around the pond wolla!
The impact of this is it does not affect the prazi as formaldehyde is amongst other things a preservative and it will have no negative effect on your filter as it’s a very low amount.
Conclusions are this:
My 100% pure Prazi I’m happy to recommend a dose rate of 10 gram to 1000-1100 gallons or you can if you wish do down to 10 gm per 850 gallons. Its filter and plant safe and no water change is needed and it’s a one shot treatment
You can if you wish dissolve this as out lined by putting the dose in a pop bottle and shake the crap out of it then adding to a bucket of pond water and spreading around the pond, or you can if you wish dissolve it readily by using 5ml of formaldhyde to this add 5 ml/cc of plain water to 5 gram of Prazi and makes a free flowing paste then let it stand for a few minutes and stir as you top up with water then add to a bucket of pond water, so the formaldehyde approach is 5, 5 and 5, if it was 15 gm you were putting in it would be 15gm prazi + 15ml formalin + 15 ml of water, if it was 30 gm it would be 30 gm of prazi plus 30 ml of formalin + 30 ml of water, get the picture? its the most you need to 100% dissolve the prazi without impacting fish or pond i suspect as is the case with flubenol and acetone as you start dealing with higher weights you would get away with less liquid.
Now I have the stuff here and the price is going to be circa £1 per gram plus a bit of delivery, I will be doing it in 10gm packs to treat 1000 gallons and 25 gm to treat 2750 uk gallons slightly less so the price for 10 gm is £14 including first class delivery and the price for 25 gram is £24 including first class delivery
Your comments as usual are welcome
Im not going to put this information out there so please feel free to steer people here for this account
Duncan
Ok here’s the deal with Praziquantel or more specifically 100% pure prazi.
Praziquantel originated in the United States where Tom Holder some years ago marketed Prazipond for Koi which was and is 100% pure prazi. it was originally and still is an equine wormer.
Then several years later came fluksolve which is 50% pure prazi which as you can see is half the strength
Dose rates:
In the States 100% pure prazi is dosed at 10gm per 1000 US gallons or 10 gm per 800 UK gallons as a US gallons is 20% less than ours its quite a strong dose compared to our approach
Flukesolve is dosed at 10gm or 50% concentration for 550 gallons.
Doc Johnson of Koivet advocates 7gm of 100%prazi to 1000 US gallons which equates to 3.5 grams to 400 uk gallons, which if you downscale it to 50% prazi is the same as flukesolve at 10 gm per 550 UK gallons, so doc Johnsons view is more in line with the Uk’s flukesolve does rate.
So it’s a bit confusing but it’s not really if you look at it logically
Now in the USA as well as using a higher dose than us they routinely dose it with Proform C, Proform C is 20% formaldehyde and 1% malachite green premix, this they say screws the flukes and just about every other parasite on the planet at the same time, the reasoning for this is as follows:
Its universally accepted that Prazi is an absolute swine to dissolve end of! And guess what it dissolves readily into? Yes preform c ! Hence some bright sparks some years back discovered you could dissolve 100% prazi into a standard pond dose of Proform c and hit everything at the same time. So it’s been Accepted in the states for years now you can if you wish dissolve one into the and hit multi parasites at the same time. I have spoken to several pond chums over the pond and they all dissolve Prazi into a standard pond dose of Proform C.
So if we come back to the dissolving problem, even flukesolve does not dissolve readily although I believe it’s better than pure prazi. In America if you want to dissolve it WITHOUT Proform c, you put the dose into a plastic litre pop bottle fill it with plain water and shake the whey out of it for 3 minutes and at least 70% of the stuff will dissolve ( this is in the prazipond instruction) then you add this to a bucket of pond water and most of the rest dissolves you then add to the pond and over a day or two you get a total dissolve. But I got to thinking about the proform C /Prazi combination and started to think I wonder if????
Right my thinking was the malachite aspect of the combo was is insignificant in the dissolving process as it’s just a salt, so it had to be the formaldehyde so I set about seeing how little you could get away with and came up with this formula
5 grams of Prazi + 5 ml of formaldehyde plus 5 ml of water mix this with vigour for 2 to 3 minutes and you get a white free flowing paste, let it stand for a 5 minutes then top up with tap water stirring as you add water and you will find you have totally dissolved the powder 100% add this to a buck of pond water and mix then spread around the pond wolla!
The impact of this is it does not affect the prazi as formaldehyde is amongst other things a preservative and it will have no negative effect on your filter as it’s a very low amount.
Conclusions are this:
My 100% pure Prazi I’m happy to recommend a dose rate of 10 gram to 1000-1100 gallons or you can if you wish do down to 10 gm per 850 gallons. Its filter and plant safe and no water change is needed and it’s a one shot treatment
You can if you wish dissolve this as out lined by putting the dose in a pop bottle and shake the crap out of it then adding to a bucket of pond water and spreading around the pond, or you can if you wish dissolve it readily by using 5ml of formaldhyde to this add 5 ml/cc of plain water to 5 gram of Prazi and makes a free flowing paste then let it stand for a few minutes and stir as you top up with water then add to a bucket of pond water, so the formaldehyde approach is 5, 5 and 5, if it was 15 gm you were putting in it would be 15gm prazi + 15ml formalin + 15 ml of water, if it was 30 gm it would be 30 gm of prazi plus 30 ml of formalin + 30 ml of water, get the picture? its the most you need to 100% dissolve the prazi without impacting fish or pond i suspect as is the case with flubenol and acetone as you start dealing with higher weights you would get away with less liquid.
Now I have the stuff here and the price is going to be circa £1 per gram plus a bit of delivery, I will be doing it in 10gm packs to treat 1000 gallons and 25 gm to treat 2750 uk gallons slightly less so the price for 10 gm is £14 including first class delivery and the price for 25 gram is £24 including first class delivery
Your comments as usual are welcome
Im not going to put this information out there so please feel free to steer people here for this account
Duncan